Human endothelial cells secrete neurotropic factors to direct axonal growth of peripheral nerves.

Grasman, Johnathan M.
Kaplan, David, 1953-

Understanding how nerves spontaneously innervate tissues or regenerate small injuries is critical to enhance material-based interventions to regenerate large scale, traumatic injuries. During embryogenesis, neural and vascular tissues form interconnected, complex networks as a result of signaling between these tissue types. Here, we report that human endothelial cells (HUVECs) secrete brain-derive... read more

Nerves, Peripheral.
Tufts University. Department of Biomedical Engineering.
Permanent URL
Original publication
Grasman, Jonathan M., and David L. Kaplan. "Human Endothelial Cells Secrete Neurotropic Factors to Direct Axonal Growth of Peripheral Nerves." Scientific Reports 7, no. 1 (June 22, 2017). doi:10.1038/s41598-017-04460-8.
ID: tufts:22483
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