Conformational Restriction of the NPF Motif to Target EHD1 and Endocytic Recycling


Abstract: The development of specific inhibitors for the long-loop recycling pathway is critical for the study of vesicle trafficking and its involvement in the spread of metastasized cancer cells. Many of the proteins involved in this pathway are difficult to target due to the large and shallow protein-protein interactions they require to function. EHD1, a C-terminal EH domain-containing protein,... read more

Tufts University. Department of Chemistry.
Permanent URL
ID: tufts:22413
To Cite: DCA Citation Guide