Genetic analysis of homologous recombination repair of DNA double-strand breaks in Drosophila melanogaster.

Thomas, Adam.

Abstract: Eukaryotic cells employ a number of pathways to ensure that their genomes are faithfully duplicated and accurately repaired when damaged. One critical pathway for the repair of DNA double strand breaks (DSBs) is homologous recombination (HR). HR involves copying DNA sequence from an intact template, often a sister chromatid, to restore genetic information lost at a DSB site. The HR pathw... read more

Tufts University. Department of Biology.
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ID: tufts:22039
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