Genetic control of DNA repeat expansions and mutagenesis.

Shah, Kartik.
2017-04-24T15:11:27.728Z

Abstract: Expansions of simple DNA repeats are known to cause several devastating neurodegenerative diseases in humans. Experimental systems mimicking large-scale human expansions have (1) proven difficult to develop and (2) been only moderately successful. Different cellular processes - replication, repair, homologous recombination and transcription, have been implicated in repeat instability in ... read more

Subjects
Tufts University. Department of Biology.
Permanent URL
http://hdl.handle.net/10427/012269
ID: tufts:22007
To Cite: DCA Citation Guide