GABRA2 POINT-MUTATION: INCREASED BINGE-LIKE AND BLUNTED DEPENDENCE-INDUCING ALCOHOL DRINKING BY MICE

Newman, Emily.
2017-04-19T18:07:25.741Z

Abstract: Alcohol use disorders have been associated with SNPs in GABRA2, the gene encoding the GABAA receptor α2-subunit in humans. Deficient GABAergic functioning is linked to impulse control disorders including intermittent explosive disorder, and to drug abuse and dependence, yet it remains unclear if α2-containing GABAA receptor sensitivity to endogenous ligands is involved in excessive alcoh... read more

Subjects
Tufts University. Department of Psychology.
Permanent URL
http://hdl.handle.net/10427/011789
ID: tufts:21264
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