Novel Lipidated Compounds for Delivery and Function.

Tarakkad Krishnaji, Subrahmanian.
2017-04-19T12:50:14.590Z

Abstract: Cells regulate gene activity by post-transcriptional silencing of the genes using small double stranded RNAs (dsRNAs). This phenomenon is called RNA interference (RNAi). In mammalian cells, RNA duplexes, termed as short interfering RNAs (siRNAs), bind to cognate mRNA sequences and based on complementarity, repress translation or cleave mRNA strands. This gene-silencing pathway can be uti... read more

Subjects
Tufts University. Department of Chemistry.
Permanent URL
http://hdl.handle.net/10427/011688
ID: tufts:21163
To Cite: DCA Citation Guide