Metabolic Engineering for the Heterologous Biosynthesis of Erythromycin A and Associated Polyketide Products in Escherichia coli.

Zhang, Haoran.
2017-04-18T14:05:42.372Z

Abstract: The natural product erythromycin is a potent and widely used antibiotic for bacterial infections. In structure, erythromycin consists of one 14-membered polyketide ring, 6-deoxy-erythronolide B (6dEB), and two sugar residues, cladinose and desosamine. Erythromycin is natively produced by a soil-dwelling bacterium Saccharopolyspora erythraea that is fastidious in its growth requirements a... read more

Subjects
Tufts University. Department of Chemical and Biological Engineering.
Permanent URL
http://hdl.handle.net/10427/011592
ID: tufts:21067
To Cite: DCA Citation Guide