Synthesis-Dependent Microhomology-Mediated End Joining: A Unifying Model For Multiple DNA Double Strand Break Repair Outcomes.

Yu, Amy.
2017-04-18T14:05:27.141Z

Abstract: DNA double-strand breaks (DSBs) are repaired by homology-directed repair or non-homologous end joining. End-joining repair can be classified as classical non-homologous end joining, which requires DNA ligase 4, or "alternative" end joining (alt-EJ), which does not. The mechanism of alt-EJ is largely uncharacterized. We show that Drosophila melanogaster DNA polymerase theta (pol theta), e... read more

Subjects
Tufts University. Department of Biology.
Permanent URL
http://hdl.handle.net/10427/011586
ID: tufts:21061
To Cite: DCA Citation Guide