Dynamic Model of Chinese Hamster Ovary Cell Metabolism in Fed-Batch Culture.Nolan, Ryan.
Abstract: In this work, the design and execution of a mechanistic metabolic model is presented that is capable of simulating extracellular metabolite concentration profiles, particularly cell density and antibody titer, throughout the course of a recombinant protein producing CHO fed-batch culture. In Chapter 2, formulation of a reaction network is described wherein a genome scale metabolic reacti... read more
- Tufts University. Department of Chemical and Biological Engineering.
- Permanent URL
|To Cite:||DCA Citation Guide|