Dynamic Model of Chinese Hamster Ovary Cell Metabolism in Fed-Batch Culture.

Nolan, Ryan.
2017-04-18T14:02:14.306Z

Abstract: In this work, the design and execution of a mechanistic metabolic model is presented that is capable of simulating extracellular metabolite concentration profiles, particularly cell density and antibody titer, throughout the course of a recombinant protein producing CHO fed-batch culture. In Chapter 2, formulation of a reaction network is described wherein a genome scale metabolic reacti... read more

Subjects
Tufts University. Department of Chemical and Biological Engineering.
Permanent URL
http://hdl.handle.net/10427/011470
ID: tufts:20946
To Cite: DCA Citation Guide