Sex differences in behavioral and neural cross-sensitization and escalated cocaine taking as a result of intermittent social defeat stress in rats.

Holly, Elizabeth.

Abstract: Brief episodes of social stress can result in cross-sensitization to cocaine in rodents, characterized by augmented locomotor activation, dopamine (DA) levels in the nucleus accumbens (NAc), and cocaine taking during a 24 hour "binge" in male rats. However, females are more vulnerable than males at each phase of cocaine addiction, and while these sex differences have been replicated in r... read more

Tufts University. Department of Psychology.
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ID: tufts:20856
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