Analysis of Aortic Valve Function in the Absence of Endothelial Retinoblastoma Protein


Abstract: Calcific aortic valve disease (CAVD) affects 2-3% of the population age over the age of 75 years. Surgical replacement remains the only treatment for CAVD, highlighting an acute need to better understand CAVD biology to develop medical treatments. The pathological process of CAVD shares phenotypic and transcriptional similarities with the physiological process of osteogenesis. Since the ... read more

Sackler School of Graduate Biomedical Sciences. Department of Genetics.
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ID: tufts:20668
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