Studies on Polyoma Middle T Antigen Signaling.Zhu, Yanni.
Abstract: The development of tumors in mice expressing transgenic polyomavirus middle T (MT) antigen in mammary cells has been intensively studied because it closely matches the progression of human breast cancer. Here I have examined the regulation of ERK by MT in mouse mammary gland epithelial cells. Stress responses are important in both the development and treatment of cancer. MT suppresses th... read more
- Sackler School of Graduate Biomedical Sciences. Department of Biochemistry.
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