A role of mitochondria in mast cell activation and possible involvement in auto-immunity.

Zhang, Bodi.

Abstract: Mast cells, derived from bone marrow, are key immune effector cells that cause allergic symptoms, regulate innate and acquired immunity, but are also involved in many autoimmune and inflammatory diseases. Mast cells participate in immune process by secreting granule-stored components, such as histamine, and de novo synthesized mediators, such as IL-6, 8 and 13 in response to allergic, ne... read more

Sackler School of Graduate Biomedical Sciences. Department of Biochemistry.
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ID: tufts:20635
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