Angiogenin promotes glioblastoma invasive growth through FOSL2-mediated upregulation of CD24 and MMP9.Yang, Hailing.
Abstract: Glioblastoma (GBM) is the most aggressive brain tumor and patients suffer from neurological debilitation and die from rapid disease progression due to the lack of effective therapeutics. The current treatment includes surgery, radiation, and chemotherapy. More recently, anti-angiogenic therapy with bevacizumab, a humanized anti-VEGF antibody, has been added and shown to improve neurologi... read more
- Sackler School of Graduate Biomedical Sciences Department of Cell, Molecular and Developmental Biology.
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