Functional Analysis of Cytoskeletal Protein Dematin in Glucose Metabolism.Wu, Jiayi.
Abstract: Dematin, a membrane-cytoskeleton associated actin-binding protein, is known to bind to human erythrocyte membrane glucose transporter, GLUT1/SLC2A1, and hence may attach and stabilize the GLUT1 to the spectrin-actin network. The headpiece domain of dematin contains actin-binding and cAMP-kinase phosphorylation sites, which are required for the stability of erythrocyte membrane. Dematin a... read more
- Sackler School of Graduate Biomedical Sciences. Department of Pharmacology and Experimental Therapeutics.
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