Functional Analysis of Cytoskeletal Protein Dematin in Glucose Metabolism.

Wu, Jiayi.
2015

Abstract: Dematin, a membrane-cytoskeleton associated actin-binding protein, is known to bind to human erythrocyte membrane glucose transporter, GLUT1/SLC2A1, and hence may attach and stabilize the GLUT1 to the spectrin-actin network. The headpiece domain of dematin contains actin-binding and cAMP-kinase phosphorylation sites, which are required for the stability of erythrocyte membrane. Dematin a... read more

Subjects
Sackler School of Graduate Biomedical Sciences. Department of Pharmacology and Experimental Therapeutics.
Permanent URL
http://hdl.handle.net/10427/011155
ID: tufts:20628
To Cite: DCA Citation Guide