Investigating the role of autophagy in TLR7-mediated SLE pathogenesis.

Weindel, Catherine.
2015

Abstract: Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease, defined by loss of B cell self-tolerance that results in production of anti-nuclear antibodies and chronic inflammation. While the initiating events in lupus development are not well defined, overexpression of the RNA-recognizing toll-like receptor (TLR)7 has been linked to SLE in humans and mice. We postulated tha... read more

Subjects
Sackler School of Graduate Biomedical Sciences. Department of Genetics.
Permanent URL
http://hdl.handle.net/10427/011147
ID: tufts:20619
To Cite: DCA Citation Guide