Activation-Induced Deaminase in Early Developing B cells and Toll-like Receptor 8 in the Etiopathology of Murine Systemic Lupus Erythematosus.

Umiker, Benjamin.
2014

Abstract: Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the presence of pathogenic IgG anti-nuclear antibodies and increased type I interferon (IFN-I) production. Increased granulopoiesis is often observed in human SLE patients; however, the mechanism by which these cells contribute to autoantibody and IFN-I production is unclear. Using 564Igi mice, which model these... read more

Subjects
Sackler School of Graduate Biomedical Sciences. Department of Immunology.
Permanent URL
http://hdl.handle.net/10427/011136
ID: tufts:20609
To Cite: DCA Citation Guide