Regulation of the Follistatin Gene by RSPO-LGR4 Signaling via Activation of the WNT/-Catenin Pathway in Skeletal Myogenesis.

Tan, Leonard.

Abstract: WNT signaling plays multiple roles in skeletal myogenesis during gestation and postnatal stages. The R spondin (RSPO) family of secreted proteins and their cognate receptors, members of leucine-rich repeat containing G protein-coupled receptor (LGR) family, have emerged as new regulatory components of the WNT signaling pathway. We previously showed that RSPO2 promoted myogenic differenti... read more

Tufts University. Department of Biology.
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ID: tufts:20592
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