Study of immune cell signaling modulation by Yersinia protein kinase A (YpkA/YopO).

Sood, Arpana.
2013

Abstract: Bacterial pathogens employ several strategies to dampen host cell immune responses. In this work we studied a secreted effector protein of the Yersinia pseudotuberculosis type-three secretion system (T3SS). We found that Yersinia protein kinase A (YpkA), employs serine-kinase activity to target immune cell signaling and dampen chemotaxis and reactive oxygen species (ROS)-production. Cell... read more

Subjects
Sackler School of Graduate Biomedical Sciences. Department of Molecular Microbiology.
Permanent URL
http://hdl.handle.net/10427/011098
ID: tufts:20571
To Cite: DCA Citation Guide