Regulation of Monocyte/Macrophage ATP-Binding Cassette Transporters and Cholesterol Efflux by Elevated Glucose and Free Fatty Acid Concentrations.

Spartano, Nicole.

Abstract: Individuals with diseases of poor glycemic control, including pre-diabetes and type 2 diabetes mellitus, are at increased risk of developing atherosclerosis, the major form of cardiovascular disease (CVD). Atherosclerotic lesion formation is promoted by monocyte/macrophage recruitment into the arterial wall and subsequent cholesterol accumulation in macrophages. However, the relationship... read more

Gerald J. & Dorothy R. Friedman School of Nutrition Science and Policy.
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