Genetic Control of Murine Schistosomiasis: In Search of Genes.Smith, Patrick.
Abstract: Infection with the trematode parasite Schistosoma mansoni results in a distinct heterogeneity of disease severity, both in humans and in an experimental mouse model. Severe disease is characterized by pronounced hepatic egg-induced granulomatous inflammation in a proinflammatory cytokine environment, while mild disease corresponds with reduced hepatic inflammation in a Th2 skewed cytokin... read more
- Sackler School of Graduate Biomedical Sciences. Department of Immunology.
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