The Role of Protease-Activated Receptor-1 and -2 Signaling in Inflammation and Vascular Injury.

Sevigny, Leila.

Abstract: Protease-activated receptors (PARs) play significant roles in various human diseases including thrombosis, sepsis, cancer, and inflammation. Attenuating the signaling of these G-protein coupled receptors holds promise for treatment of these ailments. This thesis examines the role of PAR1 and PAR2 signaling in vascular injury and inflammation. PAR1 and PAR2 are diverse receptors that play... read more

Sackler School of Graduate Biomedical Sciences. Department of Genetics.
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ID: tufts:20553
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