The role of galectin-8 in ocular immunity and autoimmunity.

Sampson, James.

Abstract: Galectins have emerged as potent immunoregulatory molecules that control chronic inflammation through distinct mechanisms. Galectin-8 (Gal-8), a tandem-repeat type galectin with unique preference for 2,3-sialylated glycans, is ubiquitously expressed, but little is known about its role in T cell differentiation. Here, we report that Gal-8 promotes the polyclonal differentiation of primary... read more

Sackler School of Graduate Biomedical Sciences. Department of Immunology.
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ID: tufts:20551
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