Alternate lifestyles of C. albicans: Immunosensing through Efg1p promotes either colonization or pathogenesis.Pierce, Jessica.
Abstract: Candida albicans is a colonizing fungus of the human gastrointestinal tract. When a host becomes immunocompromised, C. albicans can cause significant mucosal and systemic infections. The ability of C. albicans to switch between commensal and pathogenic growth is not well understood. The transcription factor Efg1p regulates morphology and virulence, but the role of Efg1p during gastrointe... read more
- Sackler School of Graduate Biomedical Sciences. Department of Molecular Microbiology.
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