Examining signaling mechanisms by which colonic pro-inflammatory cytokines modulate obesity-promoted colonic carcinogenesis.

Pfalzer, Anna.

Abstract: Colorectal cancer (CRC) is the third most common cancer and third most common cause of cancer deaths in the United States. Amongst the many risk factors for this disease is obesity: those with a BMI of 25-29.9 have a relative risk of 1.2 and 1.5 for developing CRC, while those with a BMI of 30 have a relative risk of 1.5 and 2.0 for females and males, respectively. Recent evidence sugges... read more

Gerald J. & Dorothy R. Friedman School of Nutrition Science and Policy.
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