The Role of Aconitase in the Regulation of Metabolism and Sporulation in Bacillus subtilis.Pechter, Kieran.
Abstract: Previously, it was shown that an aconitase (citB) null mutation results in a vast over-accumulation of citrate in the culture supernatant of growing Bacillus subtilis cells, a phenotype that causes secondary effects, including the hyper-expression of the citB promoter. The first chapter of this thesis, in part, reveals the mechanism of this hyper- expression: CcpC, which acts as a repres... read more
- Sackler School of Graduate Biomedical Sciences. Department of Molecular Microbiology.
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