RIPK1 and RIPK3 kinases promote cell death independent inflammation by TLR4-TRIF.Najjar, Malek.
Abstract: The innate immune response is an essential first line of defense against bacterial and viral infection. Myeloid-derived cells, such as macrophages, function as crucial components of the innate immune system in recognizing pathogen-associated molecular patterns. Cell death and inflammation are the main innate immune processes contributing to eliminate pathogen proliferation. RIPK1 and RIP... read more
- Sackler School of Graduate Biomedical Sciences. Department of Pharmacology and Experimental Therapeutics.
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