RIPK1 and RIPK3 kinases promote cell death independent inflammation by TLR4-TRIF.

Najjar, Malek.

Abstract: The innate immune response is an essential first line of defense against bacterial and viral infection. Myeloid-derived cells, such as macrophages, function as crucial components of the innate immune system in recognizing pathogen-associated molecular patterns. Cell death and inflammation are the main innate immune processes contributing to eliminate pathogen proliferation. RIPK1 and RIP... read more

Sackler School of Graduate Biomedical Sciences. Department of Pharmacology and Experimental Therapeutics.
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ID: tufts:20475
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