The kinesin-3 family motor KLP-4 regulates anterograde trafficking of GLR-1 glutamate receptors in the ventral nerve cord of C. elegans.Monteiro, Michael.
Abstract: Glutamate is the major excitatory neurotransmitter in the mammalian brain. Changes in the strength of glutamatergic synapses are thought to underlie learning and memory and to contribute to the pathology of numerous neurological diseases. The transport of glutamate receptors from the cell body to synapses contributes to the regulation of synaptic strength. We previously showed that cycli... read more
- Sackler School of Graduate Biomedical Sciences Department of Cell, Molecular and Developmental Biology.
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