Regional and cell type-specific variations in tonic GABAergic inhibition.

Lee, Vallent.

Abstract: BACKGROUND: The diversity of GABAA receptor subunits and their configurations during subunit assembly produce a variety of receptors with different functional properties. Variations in subcellular localization, GABA binding affinity, and pore kinetics give rise to two classes of GABAergic conductancephasic and tonicwith heterogeneity across brain regions and cell types. The precise roles... read more

Sackler School of Graduate Biomedical Sciences. Department of Neuroscience.
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ID: tufts:20460
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