Comparisons of the Polyomavirus Small T Antigens Demonstrate Novel Regulatory Pathways in Apoptosis and DIfferentiation.

Hwang, Justin.

Abstract: Abstract Polyomaviruses have provided many insights into control of cell physiology. Studies of their tumor antigens (Tags) have led to appreciation of the role of tyrosine phosphorylation, PI3K and p53 in oncogenic transformation. This work explores signal pathways regulated by polyomavirus small T antigen (PyST) that control differentiation and regulate cell survival in fat, muscle and... read more

Sackler School of Graduate Biomedical Sciences. Department of Biochemistry.
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ID: tufts:20379
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