Inhibition of Human Cytochromes P450 in vitro by Ritonavir and Cobicistat.

Hossain, Md Amin.
2016

Abstract: Like ritonavir, cobicistat is also a potent inhibitor of cytochrome P450 3A enzymes, including subtype CYP3A4. Both of them have the ability to inhibit liver enzymes that metabolize other medications used to treat HIV, like atazanavir, darunavir and elvitegravir. Ritonavir and cobocistat have been using in highly active antiretroviral therapy (HAART) combination for boosting activity tha... read more

Subjects
Sackler School of Graduate Biomedical Sciences. Department of Pharmacology and Experimental Therapeutics.
Permanent URL
http://hdl.handle.net/10427/010900
ID: tufts:20373
To Cite: DCA Citation Guide