Modeling Cellular Dynamics: The Germinal Center.Hawkins, Jared.
Abstract: We have developed an agent-based computer simulation framework (PathSim2) capable of modeling overall human immune system dynamics, with a focus on local cellular interactions within lymphatic tissue. Our simulation predicts that the generation and maintenance of both a naive primary follicle and an activated secondary follicle containing a germinal center (GC) can be explained by the ac... read more
- Sackler School of Graduate Biomedical Sciences. Department of Immunology.
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