Impact of Retinoblastoma Protein Loss on Osteoblast Migration and Differentiation.

Gunduz, Volkan.
2011

Abstract: The retinoblastoma protein pathway is inactivated in a wide range of human cancers. RB1 itself, however, is frequently inactivated only in a subset of tumors including retinoblastoma and osteosarcoma (OS). The fact that RB1 loss favors tumor formation in certain tissues suggests that pRB might have tissue-specific functions in addition to its central role in cell cycle regulation. Indeed... read more

Subjects
Sackler School of Graduate Biomedical Sciences. Department of Genetics.
Permanent URL
http://hdl.handle.net/10427/010887
ID: tufts:20359
To Cite: DCA Citation Guide