Novel Modulators of Rickets Receptor Mediated Signaling In Vitro and In Vivo.

Harwood, Bejamin.
2014

Abstract: My initial efforts focused on extending the utility of membrane tethered ligands (MTLs) to enable exploration of the function of rickets (rk), a Drosophila melanogaster G protein-coupled receptor (GPCR). Rk mediates wing expansion, cuticle hardening, and melanization during the transition from the pupal to adult stages. The endogenous rk ligand is bursicon, a heterodimeric cystine-knot p... read more

Subjects
Sackler School of Graduate Biomedical Sciences. Department of Genetics.
Permanent URL
http://hdl.handle.net/10427/010885
ID: tufts:20358
To Cite: DCA Citation Guide