Discovery of chromosomal factors contributing to the virulence of Yersinia pseudotuberculosis, including Fis, a regulator of resistance to reactive oxygen species.Green, Erin R.
Abstract: All three pathogenic Yersinia species share a conserved virulence plasmid that encodes a Type 3 Secretion System (T3SS) and its effectors. This system contributes to growth and virulence in mammalian infection by injecting effector proteins into innate immune cells to dismantle their bactericidal functions. However, in the absence of this plasmid, the enteric pathogen Yersinia pseudotube... read more
- Sackler School of Graduate Biomedical Sciences. Department of Molecular Microbiology.
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