A Humanized Model of Breast Cancer Metastasis to Bone Revealing Unique Roles for the Primary Tumor and Bone Microenvironment.

Goldstein, Robert.

Abstract: Approximately 200,000 new cases of breast cancer and 40,000 breast cancer deaths occur annually in the U.S., making breast cancer the most common malignancy and second leading cause of cancer death in women. Metastasis of breast cancer cells from the primary neoplasm to the bone marrow has been shown to occur in up to 70% of breast cancer cases and development of this spread to clinicall... read more

Sackler School of Graduate Biomedical Sciences. Department of Genetics.
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ID: tufts:20347
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