Characterization of Matrix Metalloprotease 1a in Tumorigenesis.

Foley, Caitlin.

Abstract: Matrix metalloproteases (MMPs) are a family of extracellular proteases that allow cells to both sense and remodel their extracellular environment through cleavage of cell surface receptors, secreted factors and matrix proteins. While proteolytic activity of MMPs is required for normal tissue homeostasis and other physiologic processes, many pathophysiologic conditions are associated with... read more

Sackler School of Graduate Biomedical Sciences. Department of Genetics.
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ID: tufts:20331
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