Regulation of Polyadenylation in Eukaryotic pre-mRNA.

Ezeokonkwo, Chukwudi.

Abstract: The processing of eukaryotic pre-mRNA is an essential step in the synthesis of mRNA in living cells. It involves a coupled cleavage and polyadenylation reaction, in which the pre-mRNA is cleaved at the cleavage site, followed by the processive addition of a poly(A) tail to the upstream pre-mRNA transcript. The poly(A) tail is essential for the stability and export of mature mRNAs from th... read more

Sackler School of Graduate Biomedical Sciences. Department of Biochemistry.
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ID: tufts:20330
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