The regulation of interferon signaling and ER stress response by different Akt isoforms.

Ezell, Scott.
2012

Abstract: The protein kinases Akt1, Akt2, and Akt3 possess non-redundant signaling properties, few of which have been investigated. Here we present evidence for an Akt1-dependent pathway that controls interferon-regulated gene expression and antiviral immunity. The target of this pathway is EMSY, an oncogenic interacting partner of BRCA2 that functions as a transcriptional repressor. Overexpressio... read more

Subjects
Sackler School of Graduate Biomedical Sciences. Department of Biochemistry.
Permanent URL
http://hdl.handle.net/10427/010854
ID: tufts:20327
To Cite: DCA Citation Guide