Cyclin-dependent kinase 6 regulates cardiac embryonic proliferation and pathological hypertrophy.

Bryan, Crystal.

Abstract: Heart failure affects 1-3% of people in the Western world and is strongly associated with cardiac hypertrophy. Studies have linked the cell cycle machinery to this process, but the role of cyclins and cyclin-dependent kinases (Cdks) remains poorly understood. This study investigates the role of the G1 cell cycle regulator Cdk6 in normal development and cardiac stress. Cdk6 acts with D-ty... read more

Sackler School of Graduate Biomedical Sciences. Department of Genetics.
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ID: tufts:20294
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