The use of translational profiling for gaining a deeper molecular understanding of memory storage in the brain.

Conley, Laurel.

Abstract: Protein translation is essential to synaptic plasticity and memory storage. Specifically, local protein translation within dendrites provides specific proteins needed at sites of synaptic activation, thereby supporting highly localized synaptic plasticity. Despite this important role for dendritic translation, there is no complete profile of dendritically translated mRNAs. Identifying th... read more

Sackler School of Graduate Biomedical Sciences. Department of Neuroscience.
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ID: tufts:20290
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