Function of Plasma Membrane V-ATPases in Breast Tumor Cell Invasion.

Capecci, Joseph.

Abstract: The vacuolar H+ ATPases (V-ATPases) are a family of ATP-driven proton pumps that couple ATP hydrolysis with translocation of protons across membranes. V-ATPases are expressed in intracellular compartments, such as endosomes and lysosomes, where they participate in processes such as membrane trafficking and protein degradation. They are also present in the plasma membrane of specialized c... read more

Sackler School of Graduate Biomedical Sciences Department of Cell, Molecular and Developmental Biology.
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