UNDERSTANDING DRUG-DRUG INTERACTION DUE TO ENZYMATIC INHIBITION USING IN VITRO APPROACHES.Cao, Lei.
Abstract: Drug-drug interaction due to enzymatic inhibition is the focus of this research. Two different projects to address separate questions of drug-drug interaction were carried out applying the in vitro approaches. In the project 1, we generated a fuller picture on the in vitro inhibitory effects of the selected anti-tuberculosis drugs on common human hepatic CYP450 and UGT enzymes in hope th... read more
- Sackler School of Graduate Biomedical Sciences. Department of Pharmacology and Experimental Therapeutics.
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