Mechanisms of Actomyosin-Mediated T Cell Activation.

Brewka, Rosemary.
2011

Abstract: Antigen recognition by the T cell receptor (TCR) complex and engagement of costimulatory ligands, such as CD28 and Very Late Antigen-4 (VLA-4), are essential for sustained activation of T lymphocytes. These receptor interactions induce extensive cytoskeletal rearrangement that forms the immune synapse and shapes discrete nucleation sites of activating SLP-76 (SH2 domain containing leukoc... read more

Subjects
Sackler School of Graduate Biomedical Sciences. Department of Immunology.
Permanent URL
http://hdl.handle.net/10427/010796
ID: tufts:20269
To Cite: DCA Citation Guide