Development of vaccinia virus based reservoir-targeted vaccines.

Bhattacharya, Debaditya.

Abstract: One of the strategies to control vector-borne diseases is to eradicate or limit the causative agent from its zoonotic reservoir. We have developed reservoir-targeted oral vaccines against two diseases: plague and Lyme disease. We have used vaccinia virus (VV) as the vector for delivery of the vaccine antigens. The plague vaccine is a recombinant VV expressing F1-V fusion antigen of Yersi... read more

Sackler School of Graduate Biomedical Sciences. Department of Molecular Microbiology.
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