The role of the TWEAK/Fn14 signaling pathway in the metabolic and inflammatory response to diet-induced obesity.

Bennett, Grace.

Abstract: Adipose tissue (AT) expansion requires a program of active tissue remodeling involving temporally-orchestrated patterns of inflammatory cell recruitment, extracellular matrix (ECM) degradation and collagen turnover that promotes adipocyte hypertrophy, adipogenesis and neovascularization. It is now appreciated that these processes become dysregulated in chronic obesity, resulting in unres... read more

Gerald J. & Dorothy R. Friedman School of Nutrition Science and Policy.
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