THE ROLE OF PLASMODIUM FALCIPARUM MALARIA IN ENDEMIC BURKITT'S LYMPHOMA PATHOGENESIS.Basu Kong, Raka-Larissa.
Abstract: Endemic Burkitt's lymphoma (eBL) is the most common pediatric cancer in sub-Saharan Africa. BL is a B cell germinal center (GC)-derived lymphoma that is characterized by a reciprocal chromosomal translocation involving the c-myc gene and an immunoglobulin (Ig) locus, resulting in the constitutive activation of the c-myc proto-oncogene. This translocation occurs via the action of the enzy... read more
- Sackler School of Graduate Biomedical Sciences. Department of Genetics.
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