CYP2E1 Activity in Cisplatin Resistant Cancer Cells.

Babsail, Hussein.
2015

Abstract: Cisplatin (CP) is an anticancer drug that kills tumor cells by interfering with DNA replication. One of the main obstacles limiting its use is intrinsic or acquired resistance development. Reactive oxygen species (ROS) have a known role in cancer cell apoptosis upon CP treatment. An excessive increase in ROS generation leads to other modes of cell death such as necrosis. Microsomal Cytoc... read more

Subjects
Sackler School of Graduate Biomedical Sciences. Department of Pharmacology and Experimental Therapeutics.
Permanent URL
http://hdl.handle.net/10427/010777
ID: tufts:20250
To Cite: DCA Citation Guide