PROTEASE-ACTIVATED RECEPTOR SIGNALING IN CELLULAR DIFFERENTIATION FOLLOWING VASCULAR AND HEPATIC INJURY.Austin, Karyn.
Abstract: Protease-activated receptors (PARs) are a family of G protein coupled receptors whose aberrant activation influences a variety of disease states including cardiovascular disease, liver fibrosis, arthritis, sepsis, and cancer. This thesis focuses on the pathologic role of PAR1 and PAR2 signaling following vascular and hepatic injury. Atherothrombotic disease remains the leading cause of d... read more
- Sackler School of Graduate Biomedical Sciences. Department of Genetics.
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