Trypanosoma cruzi co-opts myocardial neurotrophin receptors for invasion and cardiotrophism.

Aridgides, Daniel.

Abstract: Trypanosoma cruzi is an obligate intracellular parasite and the causative agent of Chagas disease. A leading cause of heart failure in the Western Hemisphere, T cruzi invasion of myocardial cells drives disease progression. Overt disease occurs only in ~30% of infected individuals, however, and even then it takes decades before symptoms appear. T cruzi exploits neurotrophin receptors Trk... read more

Sackler School of Graduate Biomedical Sciences. Department of Immunology.
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ID: tufts:20237
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